PRP vs PRFM: The Real Difference That Changes Your Results

Dr. Anya Sharma · 2026-09-15

PRP and PRFM are two popular treatments for skin rejuvenation and tissue healing. They sound similar, but they work differently. Knowing the difference can help you choose the right one for your goals. At Fresh Medical Aesthetics in Plymouth, MA, we offer both and tailor each treatment to your needs. ### What Is PRP? PRP stands for Platelet-Rich Plasma. It uses your own blood, which is spun in a centrifuge to separate the platelet-rich plasma. This plasma is full of growth factors that stimulate collagen and healing. It's then injected into the skin. PRP is used for: - Facial rejuvenation to reduce fine lines and improve texture - Hair restoration to promote thicker hair - Wound healing to speed up tissue repair PRP works with your body's natural regeneration, so results look subtle and natural. ### What Is PRFM? PRFM, or Platelet-Rich Fibrin Matrix, is an advanced version of PRP. The blood draw is the same, but PRFM adds calcium. This turns the plasma into a gel-like matrix. That matrix releases growth factors slowly over time, giving longer-lasting results. PRFM is great for: - Facial rejuvenation - Under-eye hollows - Scar reduction At our practice, we use Selphyl PRFM, which is known for its consistency and effectiveness. ### PRP vs PRFM: Key Differences When deciding between PRP and PRFM, consider these points: - **Consistency:** PRP is a liquid; PRFM is a gel that stays where it's placed. - **Duration:** PRFM releases growth factors over a longer period, so results last longer. - **Best Uses:** PRP is often used for hair and general skin rejuvenation. PRFM is better for delicate areas like under-eyes and for deeper tissue repair. Both can give you great results, but PRFM is often the go-to for more advanced needs. ### Why Choose Fresh Medical Aesthetics for PRFM? We're proud to offer Selphyl PRFM to our South Shore community. Our nurse practitioners focus on natural, evidence-based results. We prioritize safety and satisfaction. From your first consultation to your treatment plan, we make sure you feel cared for. When you choose PRFM at our practice, you get: - Expert guidance from a dedicated team - Cutting-edge technology for natural results - A personalized approach to your care If you're considering PRP or PRFM, we're here to help you decide. Contact us today to schedule a consultation.